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Chronic Inflammation

Persistent low-grade inflammation that contributes to aging, disease progression, and reduced quality of life.

Medical Disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment.

Overview

Chronic inflammation is a persistent, low-grade inflammatory state that can continue for months or years. Unlike acute inflammation (which is a healthy response to injury or infection), chronic inflammation damages tissues over time and contributes to virtually all age-related diseases.

Causes include obesity (visceral fat produces inflammatory cytokines), poor diet (processed foods, sugar, refined carbs), sedentary lifestyle, chronic stress, poor sleep, smoking, and environmental toxins.

Chronic inflammation is sometimes called "inflammaging" because it's a key driver of aging and age-related diseases including heart disease, diabetes, cancer, Alzheimer's, and autoimmune conditions. Reducing inflammation is a cornerstone of longevity medicine.

Common Symptoms

  • •Persistent fatigue
  • •Body aches and joint pain
  • •Skin problems (rashes, psoriasis, acne)
  • •Digestive issues
  • •Brain fog and poor concentration
  • •Depression and anxiety
  • •Weight gain or difficulty losing weight
  • •Frequent infections
  • •Sleep disturbances
  • •Blood sugar dysregulation
  • •Accelerated aging

Key Blood Markers

hsCRP (High-sensitivity C-reactive protein)

Elevated (>1.0 mg/L indicates higher risk)

The primary marker for systemic inflammation and cardiovascular risk

ESR (Erythrocyte Sedimentation Rate)

May be elevated

Non-specific inflammation marker - elevated in many inflammatory conditions

Ferritin

May be elevated

Also an acute phase reactant - can be elevated with inflammation even without excess iron

White Blood Cell Count

Normal to mildly elevated

May be elevated with chronic inflammation

Frequently Asked Questions

What hsCRP level indicates inflammation?
Optimal hsCRP is below 1.0 mg/L. Levels 1.0-3.0 mg/L indicate moderate cardiovascular risk. Above 3.0 mg/L indicates high risk and significant inflammation. Levels above 10 mg/L often indicate acute infection or injury.
Can diet reduce inflammation?
Yes, significantly. Anti-inflammatory diets (Mediterranean diet, whole foods, omega-3s, colorful vegetables) can reduce hsCRP by 20-40%. Eliminating processed foods, sugar, and refined carbs is especially impactful.
What is the link between inflammation and heart disease?
Inflammation plays a central role in atherosclerosis. hsCRP predicts cardiovascular events independent of cholesterol. Inflamed arterial plaques are more likely to rupture and cause heart attacks.
How long does it take to reduce inflammation?
Lifestyle changes can show measurable reductions in inflammatory markers within 2-4 weeks. Significant improvements typically occur over 2-3 months. Some people see hsCRP drop by 50% or more with diet and exercise.

Quick Facts

  • Key Markers:4
  • Common Symptoms:11

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